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Drug Name | Aphanin |
Trade Name | |
Synonyms | echinenone |
Drug Descriptions |
Aphanin is a triterpenoid derived from the plant Amoora rohituka that inhibits proliferation and induces apoptosis in cancer cells through inhibition of mutant Kras, Stat3, Akt, and Myc signaling, and regulation of reactive oxygen species (PMID: 27333990). |
DrugClasses | Akt Inhibitor (Pan) 21 c-MYC Inhibitor 12 KRAS Inhibitor 15 STAT3 Inhibitor 26 |
CAS Registry Number | 432-68-8 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Aphanin | Aphanin | 0 | 0 |