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DPP-23 is a synthetic polyphenol conjugate, (E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one, that specifically targets cancer cells by inhibiting Nrf2 and introducing ROS in the cell, which leads to apoptotic induction and potential antitumor activity (PMID: 27550943, PMID: 29928453).
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Cisplatin + DPP-23||Cisplatin DPP-23||0||0|