Drug Detail


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Drug Name A-dmDT390-bisFv(UCHT1)
Trade Name
Synonyms anti-T cell immunotoxin A-dmDT390-bisFv(UCHT1)|Resimmune
Drug Descriptions

Resimmune (A-dmDT390-bisFv(UCHT1)) comprises the diphtheria toxin catalytic and translocation domains fused to antibody fragments that target the CD3-epsilon component of the T-cell receptor, potentially resulting in increased death of CD3-epsilon expressing tumor cells (PMID: 25795722)

CAS Registry Number 1470038-56-2
NCIT ID C74004


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Therapy Name Drugs Efficacy Evidence Clinical Trials
A-dmDT390-bisFv(UCHT1) A-dmDT390-bisFv(UCHT1) 0 0
A-dmDT390-bisFv(UCHT1) + Pembrolizumab A-dmDT390-bisFv(UCHT1) Pembrolizumab 0 1

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