Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name A-dmDT390-bisFv(UCHT1)
Trade Name
Synonyms anti-T cell immunotoxin A-dmDT390-bisFv(UCHT1)|Resimmune
Drug Descriptions

Resimmune (A-dmDT390-bisFv(UCHT1)) comprises the diphtheria toxin catalytic and translocation domains fused to antibody fragments that target the CD3-epsilon component of the T-cell receptor, potentially resulting in increased death of CD3-epsilon expressing tumor cells (PMID: 25795722)

DrugClasses

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
A-dmDT390-bisFv(UCHT1) A-dmDT390-bisFv(UCHT1) 0 0
A-dmDT390-bisFv(UCHT1) + Pembrolizumab A-dmDT390-bisFv(UCHT1) Pembrolizumab 0 1


Additional content available in CKB BOOST