Drug Detail


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Drug Name Sym021
Trade Name
Synonyms Sym-021|Sym 021
Drug Descriptions

Sym021 is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 3822, PMID: 31046547, PMID: 31754392).

DrugClasses Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117
CAS Registry Number 2233593-42-3
NCIT ID C142865


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Futuximab + S095029 + Sym021 Futuximab S095029 Sym021 0 1
Modotuximab + S095029 + Sym021 Modotuximab S095029 Sym021 0 1
S095029 + Sym021 S095029 Sym021 0 1
Sym021 Sym021 0 1
Sym021 + Sym022 Sym021 Sym022 0 1
Sym021 + Sym023 Sym021 Sym023 0 1
Sym021 + Sym024 Sym021 Sym024 0 1

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