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Disarib is a small molecule inhibitor of BCL2, which targets the BH1 domain of BCL2, thereby interfering with the interaction between BCL2 and BAK, and subsequently, leading to apoptosis (PMID: 28223017).
|DrugClasses||BCL2 inhibitor 26|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Disarib + Paclitaxel||Disarib Paclitaxel||0||0|