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Drug Name BMS-986416
Trade Name
Synonyms AVID200|AVID 200|AVID-200|BMS986416|BMS 986416
Drug Descriptions

BMS-986416 (AVID200) is a TGF-beta receptor-based TGF-beta trap, which neutralizes TGF-beta1 and TGF-beta3 without interfering with TGF-beta2, resulting in decreased downstream signaling and potentially leading to increased recruitment and activation of anti-tumor T cells (Cancer Res July 1 2017 (77) (13 Supplement) 4688).

DrugClasses
CAS Registry Number 2269485-28-9
NCIT ID C159817

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Therapy Name Drugs Efficacy Evidence Clinical Trials
BMS-986416 BMS-986416 0 3
BMS-986416 + Nivolumab BMS-986416 Nivolumab 0 1


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