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Drug Name TR1801-ADC
Trade Name
Synonyms MT8633|MT 8633|TR 1801|anti-c-Met ADC TR1801|TR1801
Drug Descriptions

TR1801-ADC is an antibody-drug conjugate comprising a Met monoclonal antibody linked to a pyrrolobenzodiazepine dimer (PBD)-toxin, which delivers the toxin to Met-expressing tumor cells, potentially resulting in inhibition of DNA replication and decreased cell proliferation (PMID: 31736230).

DrugClasses MET Antibody 29
CAS Registry Number NA
NCIT ID C158513


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Gemcitabine + TR1801-ADC Gemcitabine TR1801-ADC 0 0
TR1801-ADC TR1801-ADC 0 1

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