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Drug Name ORIN1001
Trade Name
Synonyms ORIN-1001|ORIN 1001
Drug Descriptions

ORIN1001 is an inhibitor of IRE1, which binds to the RNase domain of Ire1, potentially leading to inhibition of the IRE1/XBP1 pathway and subsequent tumor growth, and may result in an immune response via repression of the immunosuppressive tumor microenvironment (NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C176578

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ORIN1001 ORIN1001 0 1
ORIN1001 + Paclitaxel ORIN1001 Paclitaxel 0 1


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