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Drug Name | PF-06939999 |
Trade Name | |
Synonyms | PF06939999|PF 06939999 |
Drug Descriptions |
PF-06939999 is an inhibitor that blocks PRMT5 methyltransferase activity, resulting in decreased histone H2A, H3, and H4 arginine mono- and di-methylation, which potentially leads to modulation of gene expression resulting in decreased tumor cell growth (NCI Drug Dictionary). |
DrugClasses | PRMT5 Inhibitor 16 |
CAS Registry Number | NA |
NCIT ID | C158100 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
PF-06939999 | PF-06939999 | 0 | 1 |