Gene Detail

Gene Symbol TYRO3
Synonyms BYK | Dtk | Etk-2 | Rek | RSE | Sky | Tif
Gene Description TYRO3, tyrosine-protein kinase receptor TYRO3, is a member of the TAM family (Tyro3, Axl, and Mer) and plays a role in regulation of the immune system and cell survival, migration, and differentiation through activation of PI3K and AKT (PMID: 30322068, PMID: 20546121). Overexpression of Tyro3 has been observed in leukemia, thyroid cancer, metastatic colorectal cancer, and melanoma (PMID: 30322068).
Entrez Id 7301
Chromosome 15
Map Location 15q15.1
Canonical Transcript NM_006293

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