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Gene | TYRO3 |
Variant | R426L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TYRO3 R426L does not lie within any known functional domains of the Tyro3 protein (UniProt.org). R426L has not been characterized in the scientific literature and therefore, its effect on Tyro3 protein function is unknown (PubMed, Apr 2024). |
Associated Drug Resistance | |
Category Variants Paths |
TYRO3 mutant TYRO3 R426L |
Transcript | NM_006293.4 |
gDNA | chr15:g.41570051G>T |
cDNA | c.1277G>T |
Protein | p.R426L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_006293.4 | chr15:g.41570051G>T | c.1277G>T | p.R426L | RefSeq | GRCh38/hg38 |
XM_017022543.2 | chr15:g.41570051G>T | c.1277G>T | p.R426L | RefSeq | GRCh38/hg38 |
NM_006293.3 | chr15:g.41570051G>T | c.1277G>T | p.R426L | RefSeq | GRCh38/hg38 |
XM_017022543.3 | chr15:g.41570051G>T | c.1277G>T | p.R426L | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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