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|Protein Effect||gain of function|
|Gene Variant Descriptions||ALK act mut indicates that this variant results in a gain of function in the Alk protein. However, the specific amino acid change has not been identified.|
|Associated Drug Resistance|
|Category Variants Paths||
ALK mutant ALK act mut
|Molecular Profile||Protein Effect||Treatment Approaches|
|ALK act mut||gain of function||ALK Inhibitor|
|ALK act mut TP53 wild-type|