Gene Variant Detail

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Gene PTEN
Variant negative
Impact List unknown
Protein Effect loss of function
Gene Variant Descriptions PTEN negative indicates a lack of the PTEN gene, mRNA, and/or protein.
Associated Drug Resistance
Category Variants Paths

PTEN mutant PTEN inact mut PTEN negative

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
PTEN negative loss of function Akt Inhibitor (Pan) Akt1 Inhibitor Akt2 Inhibitor PI3K Inhibitor (Pan) PIK3CB inhibitor
BRAF V600X PTEN neg
PTEN neg RB1 R255*
PTEN L152P PTEN neg