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Gene | ALK |
Variant | E862D |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ALK E862D lies within the extracellular domain of the Alk protein (UniProt.org). E862D has not been characterized in the scientific literature and therefore, its effect on Alk protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ALK mutant ALK E862D |
Transcript | NM_004304.5 |
gDNA | chr2:g.29232350C>G |
cDNA | c.2586G>C |
Protein | p.E862D |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004304.4 | chr2:g.29232350C>G | c.2586G>C | p.E862D | RefSeq | GRCh38/hg38 |
NM_004304.5 | chr2:g.29232350C>G | c.2586G>C | p.E862D | RefSeq | GRCh38/hg38 |
NM_004304 | chr2:g.29232350C>G | c.2586G>C | p.E862D | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
ALK E862D | unknown |