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Gene | ALK |
Variant | G746C |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ALK G746C lies within the extracellular domain of the Alk protein (UniProt.org). G746C has not been characterized in the scientific literature and therefore, its effect on Alk protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ALK mutant ALK G746C |
Transcript | NM_004304.5 |
gDNA | chr2:g.29239799C>A |
cDNA | c.2236G>T |
Protein | p.G746C |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004304.4 | chr2:g.29239799C>A | c.2236G>T | p.G746C | RefSeq | GRCh38/hg38 |
NM_004304.5 | chr2:g.29239799C>A | c.2236G>T | p.G746C | RefSeq | GRCh38/hg38 |
NM_004304 | chr2:g.29239799C>A | c.2236G>T | p.G746C | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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