Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene BRAF
Variant N581X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF N581X indicates any BRAF missense mutation that results in replacement of the asparagine (N) at amino acid 581 by a different amino acid.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF N581X

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_004333.6
gDNA chr7:g.140753392_140754187
cDNA c.1741_1743
Protein p.N581
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354609.1 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753392_140754187 c.1741_1743 p.N581 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
BRAF N581X unknown