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Gene | BRAF |
Variant | L584P |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | BRAF L584P lies within the protein kinase domain of the Braf protein (UniProt.org). L584P has been identified in the scientific literature (PMID: 31569065), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
BRAF mutant BRAF L584P |
Transcript | NM_004333.6 |
gDNA | chr7:g.140753384A>G |
cDNA | c.1751T>C |
Protein | p.L584P |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004333.6 | chr7:g.140753384A>G | c.1751T>C | p.L584P | RefSeq | GRCh38/hg38 |
NM_001354609.2 | chr7:g.140753384A>G | c.1751T>C | p.L584P | RefSeq | GRCh38/hg38 |
NM_001354609.1 | chr7:g.140753384A>G | c.1751T>C | p.L584P | RefSeq | GRCh38/hg38 |
NM_001378468.1 | chr7:g.140753384A>G | c.1751T>C | p.L584P | RefSeq | GRCh38/hg38 |
NM_004333.5 | chr7:g.140753384A>G | c.1751T>C | p.L584P | RefSeq | GRCh38/hg38 |
NM_001378470.1 | chr7:g.140753282_140753283delTTinsCC | c.1750_1751delTTinsCC | p.L584P | RefSeq | GRCh38/hg38 |
NM_001378474.1 | chr7:g.140753384A>G | c.1751T>C | p.L584P | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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