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Gene | ALK |
Variant | S1189C |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ALK S1189C lies within the protein kinase domain of the Alk protein (UniProt.org). S1189C has been identified in the scientific literature (PMID: 36506539), but has not been biochemically characterized and therefore, its effect on Alk protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ALK mutant ALK S1189C |
Transcript | NM_004304.5 |
gDNA | chr2:g.29220785G>C |
cDNA | c.3566C>G |
Protein | p.S1189C |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004304.5 | chr2:g.29220785G>C | c.3566C>G | p.S1189C | RefSeq | GRCh38/hg38 |
NM_004304.4 | chr2:g.29220785G>C | c.3566C>G | p.S1189C | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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