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Gene | ERBB3 |
Variant | R103H |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ERBB3 (HER3) R103H lies within the extracellular domain of the Erbb3 (Her3) protein (UniProt.org). R103H has been identified in the scientific literature (PMID: 29902295), but has not been biochemically characterized and therefore, its effect on Erbb3 (Her3) protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ERBB3 mutant ERBB3 R103H |
Transcript | NM_001982.4 |
gDNA | chr12:g.56085068G>A |
cDNA | c.308G>A |
Protein | p.R103H |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001982.4 | chr12:g.56085068G>A | c.308G>A | p.R103H | RefSeq | GRCh38/hg38 |
NM_001005915.1 | chr12:g.56085068G>A | c.308G>A | p.R103H | RefSeq | GRCh38/hg38 |
NM_001982.3 | chr12:g.56085068G>A | c.308G>A | p.R103H | RefSeq | GRCh38/hg38 |
NM_001005915.1 | chr12:g.56085068G>A | c.308G>A | p.R103H | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
ERBB3 R103H | unknown |