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Gene | CDK12 |
Variant | G1461C |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | CDK12 G1461C does not lie within any known functional domains of the Cdk12 protein (UniProt.org). G1461C has not been characterized in the scientific literature and therefore, its effect on Cdk12 protein function is unknown (PubMed, Jan 2024). |
Associated Drug Resistance | |
Category Variants Paths |
CDK12 mutant CDK12 G1461C |
Transcript | NM_016507.4 |
gDNA | chr17:g.39531224G>T |
cDNA | c.4381G>T |
Protein | p.G1461C |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_016507.3 | chr17:g.39531224G>T | c.4381G>T | p.G1461C | RefSeq | GRCh38/hg38 |
NM_016507.4 | chr17:g.39531224G>T | c.4381G>T | p.G1461C | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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