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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ATM S1455R||neuroblastoma||sensitive||PARP Inhibitor (Pan)||Olaparib||Preclinical - Cell culture||Actionable||In a preclinical study, Lynparza (olaparib) treatment of neuroblastoma cells in culture, transfected with Atm S1455R, resulted in decreased cell viability as compared to cells carrying wild-type Atm (PMID: 29059438).||29059438|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|