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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FLT3 F691L FLT3 D835Y||hematologic cancer||resistant||Crenolanib||Preclinical - Cell culture||Actionable||In a preclinical study, Crenolanib did not decrease cell proliferation of transformed mouse cells expressing Flt3 D835Y and Flt3 F691L, indicating F691L as a resistance mutation since D835Y was sensitive alone (PMID: 30651561).||30651561|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|