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|Molecular Profile||TP53 loss|
|Therapy||Methylprednisolone + Rituximab|
|Indication/Tumor Type||chronic lymphocytic leukemia/small lymphocytic lymphoma|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|TP53 loss||chronic lymphocytic leukemia/small lymphocytic lymphoma||sensitive||Methylprednisolone + Rituximab||Guideline||Actionable||Artisone-Wyeth (methylprednisolone) combined with Rituxan (rituximab) is indicated in the guidelines as first-line therapy and second line and subsequent therapy for chronic lymphocytic leukemia/small lymphocytic lymphoma patients with TP53 loss (NCCN.org).||detail...|
|PubMed Id||Reference Title||Details|