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Molecular Profile | AXL positive |
Therapy | ADCT-601 |
Indication/Tumor Type | lung adenocarcinoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
AXL positive | lung adenocarcinoma | sensitive | ADCT-601 | Preclinical - Cell culture | Actionable | In a preclinical study, ADCT-601 inhibited growth of an AXL-positive lung adenocarcinoma cell line in culture (PMID: 35086955). | 35086955 |
PubMed Id | Reference Title | Details |
---|---|---|
(35086955) | Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers. | Full reference... |