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Molecular Profile RAD51C inact mut
Therapy RP-3500
Indication/Tumor Type ovarian cancer
Response Type predicted - sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
RAD51C inact mut ovarian cancer predicted - sensitive RP-3500 Case Reports/Case Series Actionable In a Phase I/II trial (TRESR), RP-3500 treatment resulted in a partial response with complete resolution of the target lesion at 19 weeks in a patient with ovarian cancer harboring a RAD51C inactivating mutation (PMID: 37277454; NCT04497116). 37277454
PubMed Id Reference Title Details
(37277454) Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results. Full reference...