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Molecular Profile | NRAS Q61L |
Therapy | Belvarafenib |
Indication/Tumor Type | mucosal melanoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
NRAS Q61L | mucosal melanoma | predicted - sensitive | Belvarafenib | Case Reports/Case Series | Actionable | In a clinical case study, Belvarafenib (HM95573) treatment resulted in a partial response with a progression-free survival of 6.2 months in a mucosal melanoma patient harboring NRAS Q61L (PMID: 38470950). | 38470950 |
PubMed Id | Reference Title | Details |
---|---|---|
(38470950) | Exploring Molecular Genetic Alterations and RAF Fusions in Melanoma: A Belvarafenib Expanded Access Program in Patients with RAS/RAF-Mutant Melanoma. | Full reference... |