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Molecular Profile | BRAF V600E |
Therapy | Ravoxertinib |
Indication/Tumor Type | melanoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E | melanoma | sensitive | Ravoxertinib | Preclinical - Cell culture | Actionable | In a preclinical study, Ravoxertinib (GDC-0994) inhibited viability and colony formation in melanoma cell lines harboring BRAF V600E in culture (PMID: 38728872). | 38728872 |
PubMed Id | Reference Title | Details |
---|---|---|
(38728872) | The ERK inhibitor GDC-0994 selectively inhibits growth of BRAF mutant cancer cells. | Full reference... |