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Molecular Profile DNMT3A mutant
Therapy N/A
Indication/Tumor Type acute myeloid leukemia
Response Type not applicable

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
DNMT3A mutant acute myeloid leukemia not applicable N/A Clinical Study Prognostic In clinical analyses, mutations in DNMT3A were associated with poor prognosis and shorter overall survival in patients with acute myeloid leukemia (PMID: 22490330, PMID: 21881046, PMID: 21670448). 22490330 21881046 21670448
PubMed Id Reference Title Details
(22490330) Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia. Full reference...
(21881046) Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia. Full reference...
(21670448) Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia. Full reference...