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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|DNMT3A mutant||acute myeloid leukemia||not applicable||N/A||Clinical Study||Prognostic||In clinical analyses, mutations in DNMT3A were associated with poor prognosis and shorter overall survival in patients with acute myeloid leukemia (PMID: 22490330, PMID: 21881046, PMID: 21670448).||22490330 21881046 21670448|
|PubMed Id||Reference Title||Details|
|(22490330)||Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia.||Full reference...|
|(21881046)||Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia.||Full reference...|
|(21670448)||Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.||Full reference...|