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|Profile Treatment Approach Name||MEK inhibitor (Pan)|
|Profile Name||MAP2K1 E41_L54del|
|Drug Class||MEK inhibitor (Pan) 23|
|PubMed Id||Reference Title||Details|
|(18632602)||Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma.||Full reference...|
|(18223206)||Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy.||Full reference...|