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Title | GBR1302: a BEAT bispecific antibody for the treatment of HER2 positive cancers | ||||||||||||
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URL | https://www.ejcancer.com/article/S0959-8049(14)70265-5/abstract | ||||||||||||
Abstract Text | European Journal of Cancer, Vol. 50, 48 (abst nr. 139) |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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GBR1302 | GBR 1302|GBR-1302 | CD3 Antibody 92 HER2 (ERBB2) Antibody 72 | GBR1302 is a bispecific antibody that targets both ERBB2 (HER2) and CD3, which may have anti-tumor activity against ERBB2 (HER2)-positive tumors (European Journal of Cancer, Vol. 50, 48 (abst nr. 139), PMID: 32054397). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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