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Ref Type
PMID
Authors
Title GBR1302: a BEAT bispecific antibody for the treatment of HER2 positive cancers
URL https://www.ejcancer.com/article/S0959-8049(14)70265-5/abstract
Abstract Text European Journal of Cancer, Vol. 50, 48 (abst nr. 139)

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
GBR1302 GBR1302 0 2
Drug Name Trade Name Synonyms Drug Classes Drug Description
GBR1302 GBR 1302|GBR-1302 CD3 Antibody 92 HER2 (ERBB2) Antibody 72 GBR1302 is a bispecific antibody that targets both ERBB2 (HER2) and CD3, which may have anti-tumor activity against ERBB2 (HER2)-positive tumors (European Journal of Cancer, Vol. 50, 48 (abst nr. 139), PMID: 32054397).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References