Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|HPN536||HPN-536|HPN 536||MSLN Antibody 5||HPN536 is a tri-specific molecule that binds to and targets MSLN and CD3 epsilon (CD3e), as well as serum albumin, which redirects activated T-lymphocytes against MSLN-expressing tumor cells, potentially resulting in lysis of tumor cells expressing MSLN (Cancer Res 2018;78(13 Suppl):Abstract nr 1781).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT03872206||Phase Ib/II||HPN536||Study of HPN536 in Patients With Advanced Cancers Associated With Mesothelin Expression||Recruiting||USA||0|