Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|NGM120||NGM-120|NGM 120|GFRAL Antagonistic Monoclonal Antibody NGM120||NGM120 is a monoclonal antibody that targets glial-cell-derived neurotrophic factor (GDNF) family receptor alpha-like (GFRAL), which inhibits binding of its ligand GDF15 and downstream signaling (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT04068896||Phase I||NGM120||Study of NGM120 in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy||Recruiting|