Therapy Detail

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Therapy Name ALLO-501A
Synonyms
Therapy Description

ALLO-501A are allogenic CD52 negative T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19, a tumor cell surface protein, which potentially results in tumor cell lysis via binding to CD19-expressing tumor cells (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ALLO-501A ALLO 501A|ALLO501A|Allogeneic Anti-CD19 CAR T-cells ALLO-501A ALLO-501A are allogenic CD52 negative T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19, a tumor cell surface protein, which potentially results in tumor cell lysis via binding to CD19-expressing tumor cells (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04416984 Phase Ib/II ALLO-501A ALLO-647 + Cyclophosphamide + Fludarabine Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma (ALPHA-2) (ALPHA-2) Recruiting USA 0


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