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Therapy Name Omburtamab I-124
Synonyms
Therapy Description

Omburtamab I-124 is a B7-H3 (CD276) glycoprotein targeting monoclonal antibody radiolabeled with Iodine 124, which has potential antitumor activity against CD276-expressing tumor cells (PMID: 31405921; J Clin Oncol. 37, no. 15_suppl).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Omburtamab I-124 Iodine I 124 Omburtamab|Iodine I 124 MOAB 8H9 CD276 Antibody 8 Omburtamab I-124 is a B7-H3 (CD276) glycoprotein targeting monoclonal antibody radiolabeled with Iodine 124, which has potential antitumor activity against CD276-expressing tumor cells (PMID: 31405921; J Clin Oncol. 37, no. 15_suppl).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01502917 Phase I Omburtamab I-124 Convection-Enhanced Delivery of 124I-Omburtamab for Patients With Non-Progressive Diffuse Pontine Gliomas Previously Treated With External Beam Radiation Therapy Completed USA 0


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