Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|BNT141||BNT-141|BNT 141||BNT141 consists of an mRNA encoding an anti-CLDN18.2 monoclonal antibody contained within a lipid nanoparticle, which may lead to inhibition of tumor-expressed CLDN18.2, potentially resulting in tumor cell death (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT04683939||Phase Ib/II||BNT141 BNT141 + Gemcitabine + Nab-paclitaxel||Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors||Recruiting||USA | ESP | CAN||0|