Therapy Detail

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Therapy Name CART-EGFR-IL13Ra2 cells
Synonyms
Therapy Description

CART-EGFR-IL13Ra2 are autologous T-lymphocytes engineered to express both EGFR epitope 806 and IL13Ra2, which potentially induce toxicity in tumor cells expressing EGFRvIII and IL13Ra2 (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CART-EGFR-IL13Ra2 cells CART-EGFR-IL13Ra2 cells are autologous T-lymphocytes engineered to express chimeric antigen receptors (CARs) that target EGFR epitope 806 and IL13Ra2, which potentially induce toxicity in tumor cells expressing EGFR vIII or IL13Ra2 (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05168423 Phase I CART-EGFR-IL13Ra2 cells CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM Recruiting USA 0


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