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Therapy Name | AttIL12 T-cells |
Synonyms | |
Therapy Description |
AttIL12 T-cells are T-lymphocytes engineered to express membrane-anchored IL12 targeted to cell-surface vimentin (CSV), which potentially induce cytotoxicity in CSV-expressing tumor cells, enhance antitumor immune response, and inhibit tumor growth (PMID: 35027427). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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AttIL12 T-cells | AttIL12 armed T cells|attIL12-expressing T-cells | AttIL12 T-cells are T-lymphocytes engineered to express membrane-anchored IL12 targeted to cell-surface vimentin (CSV), which potentially induce cytotoxicity in CSV-expressing tumor cells, enhance antitumor immune response, and inhibit tumor growth (PMID: 35027427). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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