Therapy Detail

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Therapy Name Olmutinib
Synonyms
Therapy Description

Olmutinib (BI1482694, HM61713) is a third-generation EGFR inhibitor that inhibits activating mutations in EGFR, including those occurring with T790M, and spares wild-type EGFR, potentially resulting in decreased tumor growth (PMID: 25027951, PMID: 25521095, PMID: 30356705).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Olmutinib HM61713|BI 1482694|BI1482694|BI-1482694 EGFR Inhibitor 3rd gen 20 Olmutinib (BI1482694, HM61713) is a third-generation EGFR inhibitor that inhibits activating mutations in EGFR, including those occurring with T790M, and spares wild-type EGFR, potentially resulting in decreased tumor growth (PMID: 25027951, PMID: 25521095, PMID: 30356705, PMID: 32830792, PMID: 32679450).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status
NCT02485652 Phase II Olmutinib Phase II Trial of HM61713 for the Treatment of >= 2nd Line T790M Mutation Positive Adenocarcinoma of the Lung Active, not recruiting


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