Therapy Detail
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| Therapy Name | Mifepristone |
| Synonyms | |
| Therapy Description |
Korlym (Mifepristone) is a progesterone receptor antagonist, which may inhibit cellular proliferation and induce apoptosis (PMID: 23180967). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Mifepristone | Korlym | Corlux|Mifepriston | Hormone - Anti-progestins 6 | Korlym (Mifepristone) is a progesterone receptor antagonist, which may inhibit cellular proliferation and induce apoptosis (PMID: 23180967). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02012296 | Phase Ib/II | Mifepristone Enzalutamide | Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer | Completed | USA | 0 |
| NCT02642939 | Phase II | Mifepristone | Study of Oral Mifepristone as Salvage Therapy in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer | Terminated | USA | 0 |
| NCT02046421 | Phase I | Mifepristone Carboplatin + Gemcitabine | Carboplatin, Gemcitabine Hydrochloride, and Mifepristone in Treating Patients With Advanced Breast Cancer or Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer | Completed | USA | 0 |
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