Therapy Detail

Therapy Name Imalumab
Synonym
Therapy Description

Imalumab is a monoclonal antibody binds to and inhibits macrophage migration inhibitory factor (MIF) signaling therefore inhibits tumor cell proliferation (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Imalumab Imalumab is a monoclonal antibody binds to and inhibits macrophage migration inhibitory factor (MIF) signaling therefore inhibits tumor cell proliferation (NCI Drug Dictionary).
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Clinical Trial Phase Therapies Title Recruitment Status
NCT02540356 Phase Ib/II Imalumab Phase 1/2a Two-Arm Dose-Escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer Terminated
NCT02448810 Phase II Fluorouracil + Leucovorin Imalumab Panitumumab Phase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal Cancer Terminated