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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|YM155||YM-155||BIRC5 Inhibitor 1||YM155 is a small molecule inhibitor of BIRC5 (survivin), which may result in tumor regression and growth inhibition (PMID: 17804712).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||triple-receptor negative breast cancer||not applicable||YM155||Preclinical - Cell culture||Actionable||In a preclinical study, YM155 induced complete growth inhibition of triple-receptor negative breast cancer cells in culture (PMID: 27872098).||27872098|
|Unknown unknown||esophagus squamous cell carcinoma||not applicable||YM155||Preclinical - Cell line xenograft||Actionable||In a preclinical study, treatment with YM155 induced non-apoptotic cell death in esophageal squamous cell carcinoma (ESCC) cell lines in culture, and inhibited tumor growth in ESCC cell line xenograft models (PMID: 26090615).||26090615|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|