Therapy Detail

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Therapy Name Farletuzumab
Synonyms
Therapy Description

Farletuzumab (MORab003) is a monoclonal antibody that binds to FolR1, resulting in decreased interaction between FolR1 and Lyn, as well as increased antibody-dependent cytotoxicity and tumor cell lysis (PMID: 26063635, PMID: 30268765).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Farletuzumab MORAb-003 FOLR1-targeted Therapy 19 Farletuzumab (MORab003) is a monoclonal antibody that binds to FolR1, resulting in decreased interaction between FolR1 and Lyn, as well as increased antibody-dependent cytotoxicity and tumor cell lysis (PMID: 26063635, PMID: 30268765).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02289950 Phase II Farletuzumab A Study to Assess the Efficacy and Safety of Farletuzumab (MORAb 003) in Combination With Carboplatin Plus Paclitaxel or Carboplatin Plus Pegylated Liposomal Doxorubicin (PLD) in Subjects With Low CA125 Platinum-Sensitive Ovarian Cancer Completed USA | ITA | GBR | ESP | DEU | BEL 1


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