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HMPL-689 is a specific inhibitor of PIK3CD, which blocks PI3K/AKT signaling and B-cell activation to prevent cell proliferation (NCI Drug Dictionary).
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|HMPL-689||HMPL689|HMPL 689||PIK3CD inhibitor 26||HMPL-689 is a specific inhibitor of PIK3CD, which blocks PI3K/AKT signaling and B-cell activation to prevent cell proliferation (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT03786926||Phase Ib/II||HMPL-689||Trial to Evaluate the Safety and Pharmacokinetics of HMPL-689 in Patients With Lymphomas||Recruiting||USA | ITA | FRA | ESP||2|