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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|PRT318||PRT-060318||SYK Inhibitor 13||PRT318 is a selective inhibitor of SYK, which leads to decreased B-cell receptor signaling and decreased tumor cell viability (PMID: 22362000).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||chronic lymphocytic leukemia||not applicable||PRT318||Preclinical||Actionable||In a preclinical study, treatment with PRT318 resulted in increased apoptosis and decreased migration of primary chronic lymphocytic leukemia cells in culture (PMID: 22362000).||22362000|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|