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Therapy Name | Sirtinol |
Synonyms | |
Therapy Description |
Sirtinol inhibits SIRT1 and SIRT2, with higher activity towards SIRT2, which may result in decreased tumor cell growth (PMID: 25486469). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Sirtinol | SIRT1 Inhibitor 5 SIRT2 Inhibitor 5 | Sirtinol inhibits SIRT1 and SIRT2, with higher activity towards SIRT2, which may result in decreased tumor cell growth (PMID: 25486469, PMID: 32377734). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
Unknown unknown | melanoma | not applicable | Sirtinol | Preclinical | Actionable | In a preclinical study, Sirtinol inhibited growth of human melanoma cell lines in culture (PMID: 25486469). | 25486469 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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