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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|GS87||GSK3 Inhibitor (Pan) 2||GS87 inhibits GSK3, resulting in decreased downstream signaling and increased differentiation and reduced growth of acute myeloid leukemia cells (PMID: 27196775).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||acute myeloid leukemia||not applicable||GS87||Preclinical||Actionable||In a preclinical study, treatment with GS87 induced terminal differentiation and inhibited growth of acute myeloid leukemia (AML) cell lines in culture and resulted in increased survival and decreased disease burden in mouse models of AML (PMID: 27196775).||27196775|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|