Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Therapy Name | APS-2-79 |
Synonyms | |
Therapy Description |
APS-2-79 is a small molecule that stabilizes the inactive conformation of kinase suppressor of ras (KSR), resulting in decreased MAPK signaling, and potentially resulting in increased sensitivity to MAPK inhibitors in RAS mutant tumors (PMID: 27556948). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
APS-2-79 | APS-2-79 is a small molecule that stabilizes the inactive conformation of kinase suppressor of ras (KSR), resulting in decreased MAPK signaling, and potentially resulting in increased sensitivity to MAPK inhibitors in RAS mutant tumors (PMID: 27556948). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|