Therapy Detail

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Therapy Name BMS-986148
Synonyms
Therapy Description

BMS-986148 is a a monoclonal antibody against mesothelin (MSLN) in conjugation with an undisclosed cytotoxic drug, which may results in cytotoxic effects in of mesothelin-expressing tumor cells (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BMS-986148 BMS986148|BMS 986148 MSLN Antibody 6 BMS-986148 is a an antibody-drug conjugate (ADC) comprising a monoclonal antibody against mesothelin (MSLN) linked to the anti-microtubule agent tubulysin, which may results in cytotoxic effects in mesothelin-expressing tumor cells (PMID: 34615718).

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  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
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  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02341625 Phase Ib/II BMS-986148 BMS-986148 + Nivolumab A Study of BMS-986148 in Patients With Select Advanced Solid Tumors Terminated USA | ITA | CAN | BEL 3


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