Therapy Detail
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| Therapy Name | BMS-986148 |
| Synonyms | |
| Therapy Description |
BMS-986148 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against mesothelin (MSLN) linked to the anti-microtubule agent tubulysin, which may result in cytotoxic effects in mesothelin-expressing tumor cells (PMID: 34615718). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BMS-986148 | BMS986148|BMS 986148 | MSLN Antibody 10 | BMS-986148 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against mesothelin (MSLN) linked to the anti-microtubule agent tubulysin, which may result in cytotoxic effects in mesothelin-expressing tumor cells (PMID: 34615718). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02341625 | Phase Ib/II | BMS-986148 BMS-986148 + Nivolumab | A Study of BMS-986148 in Patients With Select Advanced Solid Tumors | Terminated | USA | NLD | ITA | GBR | CAN | BEL | AUS | 0 |
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