Therapy Detail

Therapy Name enobosarm
Synonyms
Therapy Description

Ostarine (enobosarm) is a nonsteroidal selective androgen receptor modulator that mimics testosterone function, which is currently used to treat cachexia in cancer patients (PMID: 24490605).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
enobosarm Ostarine GTx-024 Ostarine (enobosarm) is a nonsteroidal selective androgen receptor modulator that mimics testosterone function, which is currently used to treat cachexia in cancer patients (PMID: 24490605).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status
NCT02463032 Phase II enobosarm Efficacy and Safety of GTx-024 in Patients With ER+/AR+ Breast Cancer Active, not recruiting
NCT02368691 Phase II enobosarm Efficacy and Safety of GTx-024 in Patients With Androgen Receptor-Positive Triple Negative Breast Cancer (AR+ TNBC) Terminated
NCT02746328 Phase II enobosarm Add-on Study for Protocol G200802 (NCT02463032): Effect of GTx-024 on Maximal Neuromuscular Function and Lean Body Mass Completed


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