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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|DS-8273a||DS-8273a is a monoclonal antibody that activates DR5 signaling, which may lead to tumor cell apoptosis (PMID: 28050790).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Advanced Solid Tumor||not applicable||DS-8273a||Phase I||Actionable||In a Phase I trial, DS-8273a demonstrated safety and preliminary efficacy, resulted in decreased myeloid derived suppressor cells in a subset of patients, but no objective response (PMID: 28050790).||28050790|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|